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TNF-a Mouse mAb

Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.

Alternative Name(s)

TNF-alpha; TNF-a; Cachectin; Tumor necrosis factor; TNFA; TNFSF2; tnf alpha;

Application

ELISA

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UNIprot

P01375

clonality

Monoclonal

reactivity

Human

Research area

Immunology

source

Mouse

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

TNF-a Mouse mAb

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