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TMPRSS2-ERG

The high prevalence of TMPRSS2-ERG rearrangements (～60%) in prostate cancer (CaP) leads to androgenic induction of the ETS-related gene (ERG) expression. However, the biological functions of ERG overexpression in CaP remain to be understood. ERG knockdown in TMPRSS2-ERG expressing CaP cells induced striking morphological changes and inhibited cell growth both in cell culture and SCID mice.

Alternative Name(s)

TMPRSS2-ERG prostate cancer specific isoform 1;

Application

WB

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UNIprot

B2Y833

clonality

Monoclonal

reactivity

Human

Research area

Others

source

Mouse

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

TMPRSS2-ERG

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