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RNF40/BRE1B mAb

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Name(s)

BRE1B95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; BRE1 E3 ubiquitin ligase homolog B; BRE1-B; BRE1B; E3 ubiquitin-protein ligase BRE1B; Rb-associated protein; RBP95; RING finger protein 40; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B; STARING;BRE1B; KIAA0661; RBP95; RNF40; STARING

Application

WB, IP, IF

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UNIprot

O75150

clonality

Monoclonal

reactivity

Human,Mouse,Rat

Research area

Chromatin Organization

source

Mouse

storage

Store at -20℃, stable for one year from the date of shipment.

RNF40/BRE1B mAb

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