RLCK176 Antibody

OsRLCK176 is a close homolog of Arabidopsis thaliana BOTRYTIS-INDUCED KINASE 1 (AtBIK1). In rice, OsRLCK176 is a central player in disease resistance. To balance growth and defense in rice, OsRLCK176 is under tight control by different immune components. We revealed that a calcium-dependent protein kinase OsCPK17 functions as a “boost” button in the rice immune system. When a pathogen threat appears, OsCPK17 is activated to promote OsRLCK176 accumulation and thereby enhance basal defense in rice. However, without danger signals, the E3 ubiquitin ligase OsPUB12 targets OsRLCK176 for recycling, thus keeping basal defense low. OsCPK17, OsPUB12, and OsRLCK176 function as a team to fine-tune trade-offs between rice growth and defense.