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RASSF1 Antibody

Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.

Alternative Name(s)

NORE2A;

Application

WB,IHC

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UNIprot

q9ns23

clonality

Monoclonal

reactivity

Human

Research area

Signal Transduction; Cancer; Cell Biology; Epigenetics And Nuclear Signaling

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

RASSF1 Antibody

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