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PTPRM Antibody

Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation (PubMed:17761881, PubMed:10753936).Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function (PubMed:21998202).

Alternative Name(s)

Receptor-type tyrosine-protein phosphatase mu; Protein-tyrosine phosphatase mu; R-PTP-mu; PTPRM; PTPRL1;

Application

WB IHC/IF

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UNIprot

P28827

clonality

Polyclonal

reactivity

Human, Mouse, Rat

Research area

Signal Transduction

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

PTPRM Antibody

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