Precision Science Group
(PSG)
PRMT4/CARM1 Mouse mAb
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling.
Alternative Name(s)
Histone arginine methyltransferase CARM 1; Histone arginine methyltransferase CARM1; PRMT4; Protein arginine N methyltransferase 4;
Application
WB,IP
UNIprot
Q86X55
clonality
Monoclonal
reactivity
Human,Mouse
Research area
Cancer; Cell Biology; Epigenetics And Nuclear Signaling; Metabolism; Signal Transduction
source
Mouse
storage
Store at -20 ℃. Stable for 12 months from date of receipt.
PRMT4/CARM1 Mouse mAb