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PNLDC1 Antibody

3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails (PubMed:27515512).Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (PubMed:27515512).May act as a regulator of multipotency in embryonic stem cells (By similarity).Is a critical factor for proper spermatogenesis, involved in pre-piRNAs processing to generate mature piRNAs (PubMed:34347949).

Alternative Name(s)

dJ195P10.2;FLJ40240;MGC138451;poly(A)-specific ribonuclease (PARN)-like domain containing 1;poly(A)-specific ribonuclease PARN-like domain-containing protein 1; PNLDC1;

Application

WB IHC/IF

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UNIprot

Q8NA58

clonality

Polyclonal

reactivity

Human, Mouse, Rat

Research area

Epigenetics And Nuclear Signaling

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

PNLDC1 Antibody

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