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Phospho-Smad3 (S423 + S425) Antibody

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription.

Alternative Name(s)

JV15-2, MAD-3, MADH3, Mad3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMAD 3, Smad 3

Application

WB,IHC,ICC/IF

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UNIprot

p84022

clonality

Monoclonal

reactivity

Human,Mouse

Research area

Signal Transduction

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-Smad3 (S423 + S425) Antibody

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