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Phospho-Raf1 (S259) Antibody

Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

Alternative Name(s)

C-Raf; CRAF; Protein kinase raf 1; RAF1; Raf proto-oncogene serine/threonine-protein kinase; kinase Raf1;

Application

WB,IHC

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UNIprot

p04049

clonality

Monoclonal

reactivity

Human,Mouse,Rat

Research area

Signal Transduction

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-Raf1 (S259) Antibody

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