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Phospho-PP2A alpha (Y307) Antibody

PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

Alternative Name(s)

eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786

Application

WB,IHC,ICC/IF,IP

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UNIprot

p67775

clonality

Monoclonal

reactivity

Human,Mouse,Rat

Research area

Cell Biology

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-PP2A alpha (Y307) Antibody

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