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Phospho-MSK1 (S376) Antibody

Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.

Alternative Name(s)

90 kDa ribosomal protein S6 kinase polypeptide 5; EC 2.7.11.1; KS6A5; MSPK1; Nuclear mitogen- and stress-activated protein kinase-1; RLPK; RPS6KA5; kinase MSK1; ribosomal protein S6 kinase;

Application

WB,IHC,ICC,IP

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UNIprot

o75582

clonality

Monoclonal

reactivity

Human,Rat

Research area

Signal Transduction

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-MSK1 (S376) Antibody

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