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Phospho-MLKL (S358) Antibody

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Alternative Name(s)

hMLKL; Mlkl;

Application

WB,IHC

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UNIprot

q8nb16

clonality

Monoclonal

reactivity

Human

Research area

Signal Transduction

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-MLKL (S358) Antibody

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