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Phospho-MEK1 (S298) Antibody

Activation of MEK1 and MEK2 occurs through phosphorylation of two serine residues at positions 217 and 221, located in the activation loop of subdomain VIII, by Raf-like molecules. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

Alternative Name(s)

Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K1; MEK-1; PRKMK1;

Application

WB,IHC,ICC/IF

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UNIprot

q02750

clonality

Monoclonal

reactivity

Human,Mouse,Rat

Research area

Signal Transduction

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-MEK1 (S298) Antibody

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