Precision Science Group
(PSG)
Phospho-hnRPD(Ser83) Antibody
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
Alternative Name(s)
ARE element RNA-binding protein AUF1, AU-rich element RNA-binding protein 1, AUF1, HNRPD, Heterogeneous nuclear ribonucleoprotein D, Heterogeneous nuclear ribonucleoprotein D0, ROD
Application
WB,IHC,IF/ICC
UNIprot
Q14103
clonality
Polyclonal
reactivity
Human,Mouse,Rat
Research area
Epigenetics And Nuclear Signaling
source
Rabbit
storage
Store at -20 ℃. Stable for 12 months from date of receipt.
Phospho-hnRPD(Ser83) Antibody