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Phospho-hnRPD(Ser83) Antibody

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.

Alternative Name(s)

ARE element RNA-binding protein AUF1, AU-rich element RNA-binding protein 1, AUF1, HNRPD, Heterogeneous nuclear ribonucleoprotein D, Heterogeneous nuclear ribonucleoprotein D0, ROD

Application

WB,IHC,IF/ICC

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UNIprot

Q14103

clonality

Polyclonal

reactivity

Human,Mouse,Rat

Research area

Epigenetics And Nuclear Signaling

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-hnRPD(Ser83) Antibody

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