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Phospho-Histone H2A.X (S139) Antibody

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Alternative Name(s)

H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X;

Application

WB,IHC,ICC/IF,IP

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UNIprot

p16104

clonality

Monoclonal

reactivity

Human,Mouse,Rat

Research area

Epigenetics And Nuclear Signaling

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-Histone H2A.X (S139) Antibody

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