Precision Science Group
(PSG)
Phospho-ATF2 (T71) Antibody
The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71.
Alternative Name(s)
ATF2, Activating 2, CREB2, CREBP1, Cyclic-AMP-dependent ATF-2, HB16, MXBP protein, cAMP response element binding protein CRE-BP1;
Application
WB,ICC/IF,IP
UNIprot
p15336
clonality
Monoclonal
reactivity
Human
Research area
Epigenetics And Nuclear Signaling
source
Rabbit
storage
Store at -20 ℃. Stable for 12 months from date of receipt.
Phospho-ATF2 (T71) Antibody