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Phospho-4E-BP1 (Thr45) Antibody

4E-BP1 binds to eIF4E, preventing its assembly into the EIF4F complex and inhibiting cap-dependent translation. Phosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation.

Alternative Name(s)

4EBP1, EIF4EBP1, Eukaryotic translation initiation factor 4E binding protein 1, Insulin-stimulated EIF-4E binding protein PHAS-I, P/OKCL.6, PHAS-1, PHAS-I

Application

WB,IHC

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UNIprot

Q13541

clonality

Polyclonal

reactivity

Human,Mouse,Rat

Research area

Epigenetics And Nuclear Signaling; Metabolism

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Phospho-4E-BP1 (Thr45) Antibody

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