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PHD2 / prolyl hydroxylase Antibody

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Alternative Name(s)

EGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM-20; SM20; ZMYND6;

Application

WB,IP

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UNIprot

q9gzt9

clonality

Monoclonal

reactivity

Human

Research area

Iron Storage

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

PHD2 / prolyl hydroxylase Antibody

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