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Noxa Antibody

Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

Alternative Name(s)

APR; ATL-derived; NOXA; Pmaip1; Protein Noxa;

Application

WB

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UNIprot

q13794

clonality

Monoclonal

reactivity

Human

Research area

Apoptosis; Antiviral Defense; Dna Damage

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Noxa Antibody

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