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MYLK Antibody

Regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessary for physiological and asthmatic airway resistance.

Alternative Name(s)

deglutamylated form; DKFZp686I10125; EC 2.7.11.18; FLJ12216; Kinase related protein; Kinase-related protein; KRP; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; MYLK; MYLK_HUMAN; MYLK1; Myosin light chain kinase; Myosin light polypeptide kinase; OTTHUMP00000180642; OTTHUMP00000180643; smMLCK; smooth muscle; Smooth muscle myosin light chain kinase; Telokin;

Application

WB, IP

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UNIprot

Q28824, Q15746

clonality

Monoclonal

reactivity

Cow, Human, Mouse, Rat

Research area

Others

source

Mouse

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

MYLK Antibody

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