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KDM1/LSD1 Mouse mAb

Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3,thereby acting as a coactivator or a corepressor,depending on the context.Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.Acts as a corepressor by mediating demethylation of H3K4me,a specific tag for epigenetic transcriptional activation.

Alternative Name(s)

KDM1;AOF2;BHC110;KIAA0601;LSD1; KDM1A;

Application

WB,ICC,IP

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UNIprot

O60341

clonality

Monoclonal

reactivity

Human,Monkey

Research area

Epigenetics And Nuclear Signaling

source

Mouse

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

KDM1/LSD1 Mouse mAb

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