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HP1-α Mouse mAb

Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR).

Alternative Name(s)

CBX5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha;

Application

WB,IHC,ICC

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UNIprot

P45973

clonality

Monoclonal

reactivity

Human,Mouse

Research area

Epigenetics And Nuclear Signaling

source

Mouse

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

HP1-α Mouse mAb

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