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HK2 antibody

Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:23185017, PubMed:26985301, PubMed:29298880).Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed:29298880).Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis (PubMed:18350175).

Alternative Name(s)

Hexokinase-2; Hexokinase type II ; Hexokinase-B; Muscle form hexokinase ;

Application

WB,IHC/IF

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UNIprot

P52789

clonality

Polyclonal

reactivity

Human, Mouse, Rat, Pig, Goat

Research area

Signal Transduction; Cancer; Metabolism; Cardiovascular

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

HK2 antibody

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