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Hamartin Antibody

In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

Alternative Name(s)

Hamartin; kiaa0243; LAM; TSC; Tsc1; Tuberous sclerosis 1;

Application

WB,IHC,ICC/IF,FCM

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UNIprot

q92574

clonality

Monoclonal

reactivity

Human

Research area

Cell Biology

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Hamartin Antibody

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