Precision Science Group
(PSG)
FUS Antibody
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
Alternative Name(s)
75 kDa DNA-pairing protein; fus-like protein; fused in sarcoma; fusion gene in myxoid liposarcoma; fusion, derived from t(12;16) malignant liposarcoma; heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; Oncogene FUS; Oncogene TLS; pigpen protein; POMp75; Protein pigpen; RNA-binding protein FUS; translocated in liposarcoma; Translocated in liposarcoma protein; ALS6; D430004D17Rik; D930039C12Rik; ETM4; FUS; FUS1; HNRNPP2; POMP75; TLS;
Application
WB, IP
UNIprot
Q6J4Y8, P35637
clonality
Monoclonal
reactivity
Chicken, Human, Mouse, Rat
Research area
Others
source
Mouse
storage
Store at -20 ℃. Stable for 12 months from date of receipt.
FUS Antibody