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FAS Antibody

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Alternative Name(s)

Apo-1, CD95, FasL receptor, TNFRSF6, TNR6, apoptosis-mediating surface antigen FAS, tumor necrosis factor receptor superfamily member 6

Application

WB,IHC

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UNIprot

P25445

clonality

Polyclonal

reactivity

Human

Research area

Cell Biology

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

FAS Antibody

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