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EGFR mAb

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Alternative Name(s)

Epidermal growth factor receptoravian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth f; Epidermal growth factor receptor; erb-b2 receptor tyrosine kinase 1; ERBB; ERBB1; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; waved 2

Application

WB

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UNIprot

P00533

clonality

Monoclonal

reactivity

Human,Mouse,Rat

Research area

Cancer; Cell Biology; Microbiology; Signal Transduction; Epigenetics And Nuclear Signaling

source

Mouse

storage

Store at -20℃, stable for one year from the date of shipment.

EGFR mAb

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