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Cyclin D2 Mouse mAb

Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition.Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase.

Alternative Name(s)

CCND 2; CCND2; CyclinD2; G1/S specific cyclin D2; G1/S-specific cyclin-D2;

Application

WB

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UNIprot

P30279

clonality

Monoclonal

reactivity

Human

Research area

Cell Biology

source

Mouse

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Cyclin D2 Mouse mAb

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