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Cdc23/APC8 Antibody

Anaphase-promoting complex subunit 8 (APC8, CDC23) is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16). APC8 protein associates with APC3 and APC6 to facilitate recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. Research studies suggest that APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth.

Alternative Name(s)

CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8;

Application

WB,ICC/IF

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UNIprot

q9ujx2

clonality

Monoclonal

reactivity

Human,Mouse,Rat

Research area

Cell Biology

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

Cdc23/APC8 Antibody

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