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c-Fos Mouse mAb

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor.In the heterodimer,FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites.On TGF-beta activation,forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling.

Alternative Name(s)

activator protein 1; AP-1; C-FOS; cellular oncogene c-fos; Cellular oncogene fos; FOS; G0/G1 switch regulatory protein 7; G0S7;

Application

WB

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UNIprot

P01100

clonality

Monoclonal

reactivity

Human,Rat,Monkey

Research area

Neuroscience

source

Mouse

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

c-Fos Mouse mAb

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