BIK1 Antibody

Plays a central role in immune responses (PubMed:20413097, PubMed:29649442).Required to activate the resistance responses to necrotrophic pathogens, including the regulation of defense hormone expression (e.g. jasmonic acid (JA) and salicylic acid (SA)) (PubMed:16339855, PubMed:29649442).Phosphorylates FLS2 and BAK1 (PubMed:20404519, PubMed:24104392).Involved in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling, including calcium signaling, and defense responses downstream of FLS2; upon PAMP recognition, first phosphorylated by FLS2 and SIK1 prior to being monoubiquitinated by ATL44/RHA3A and ATL45/RHA3B at the plasma membrane, then internalized dynamically into endocytic compartments together with FLS2 (PubMed:20413097, PubMed:25522736, Ref.20, PubMed:30212650).Acts additively with PBL1 in PTI defenses (PubMed:20413097).