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ARL13B Antibody

Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidence is required to confirm these data.

Alternative Name(s)

ADP ribosylation factor like 13B; ADP ribosylation factor like 2 like 1; ADP-ribosylation factor-like protein 13B; ADP-ribosylation factor-like protein 2-like 1; AR13B_HUMAN; arl13b; ARL2-like protein 1; ARL2L1; JBTS8;

Application

WB IHC/IF

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UNIprot

Q3SXY8

clonality

Polyclonal

reactivity

Human, Mouse, Rat

Research area

Signal Transduction; Signaling Pathway; G Protein Signaling; Small G Proteins; Ras Family

source

Rabbit

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

ARL13B Antibody

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