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AMER2 Antibody

Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.

Alternative Name(s)

APC membrane recruitment protein 2; FAM123A;

Application

WB

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UNIprot

Q8N7J2

clonality

Monoclonal

reactivity

Human, Mouse, Rat

Research area

Wnt Signaling Pathway

source

Mouse

storage

Store at -20 ℃. Stable for 12 months from date of receipt.

AMER2 Antibody

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