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Precision Science Group
(PSG)
AMER2 Antibody
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.
Alternative Name(s)
APC membrane recruitment protein 2; FAM123A;
Application
WB
UNIprot
Q8N7J2
clonality
Monoclonal
reactivity
Human, Mouse, Rat
Research area
Wnt Signaling Pathway
source
Mouse
storage
Store at -20 ℃. Stable for 12 months from date of receipt.
AMER2 Antibody
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