MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.
MAD1 mAb
MAD1, PIG9, TP53I9, TXBP181homolog-like 1; HsMAD1; MAD1 mitotic arrest deficient-like 1; MAD1-like protein 1; mitotic arrest deficient 1-like 1; Mitotic arrest deficient 1-like protein 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1; mitotic-arrest deficient 1, yeast, homolog-like 1; PIG9; Tax-binding protein 181; TP53I9; tumor protein p53 inducible pr; tumor protein p53 inducible protein 9; TXBP181; yeast;AI173502; AW550425; MAD1; MAD1L1; PIG9; TP53I9; TXBP181