This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.
ADP/ATP translocase 2 (458) mAb
2F1, ANT2, T2, T3,Adenine nucleotide translocator 2; adenine nucleotide translocator 2 (fibroblast); ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; ADP/ATP translocase 2; ANT 2; ANT2; ATP carrier protein; ATP carrier protein 2; DP/ATP translocase 2; fibroblast isoform; N-terminally processed; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Solute carrier family 25 member 52F1; AAC2; ANT2; SLC25A5; T2; T3