The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
ACADVL mAb
ACADVACAD6; acyl-Coenzyme A dehydrogenase; acyl-Coenzyme A dehydrogenase, very long chain; LCACD; mitochondrial; MVLCAD; very long chain; Very long chain Acyl-Coa dehydrogenase; very long-chain specific acyl-CoA dehydrogenase; Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; VLCAD; VLCAD very-long-chain acyl-CoA dehydrogenase;ACAD6; ACADVL; BOS_18665; LCACD; VLCAD